Important Safety Information

This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system. To report safety concerns, please contact your local Biogen affiliate or consult your local prescribing information.

About SMA Mechanism of disease Natural History SPINRAZA^® essentials Mechanism of action Safety Posology Storage and handling Administration Technology behind SPINRAZA^®

SPINRAZA^® study programme

Overview Infantile-onset (Type I) SMA Later-onset (Type II/III) SMA Pre-symptomatic SMA Mixed SMA populations Ongoing studies Real World Evidence

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Prescribing Information en Español

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Biogen-53476. Date of preparation: April2020.

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